| Employees | Employer |
| | |
| 1839 | Eastern Illinois University
600 Lincoln Avenue
University |
| 310 | Charleston Community School District #1
K-12 Public school district |
| 180 | Vesuvius USA
North Industrial Area
Ceramic fittings for steel manufacturing |
| 178 | Charleston Transitional Facility
Improving the lives of individuals with developmental disabilities by providing residential and day program services |
| 135 | J.J. Collins & Sons, Inc
North Industrial Area
Business Forms and Commercial Web Print Manufacturer |
| 100 | Arkwright
North Industrial Area
Reprographical Supplies |
| 60 | Safety Storage
North Industrial Area
Hazaradous Storage Buildings |
| 50 | ITW Hi-Cone
North Industrial Area
Plastic multipak beverage carriers |
| 45 | Dow Chemical Company
North Industrial Area
Urethane Rigid Foam Insulation |
| 45 | Lester Building Systems
890 West State St.
Manufacturing of pre-engineered, wood frame buildings |
| 38 | Consolidated Technology
North Industrial Area
Metal Castings |
| 37 | Eastern Illinois Precast, Inc.
20005 E. State Hwy 16
Precast concrete pipe and products |
| 30 | Wausau Homes, Inc.
750 West State Street
Manufactured Homes |
